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Hereditary angioedema, or HAE, is a rare disease of the immune system, affecting an estimated 1 in 10,000 to 1 in 50,000 people around the world. HAE causes attacks of spontaneous swelling that are often painful and severe. The most common locations of HAE attacks are the:
HAE is called "hereditary" because it is caused by a genetic defect that is passed through families. When a parent has HAE, there is a 50% chance that his or her child will inherit the disease. The "angioedema" of hereditary angioedema (HAE) refers to a swelling of skin similar to hives but, unlike hives, the swelling in HAE is sometimes below the skin's surface and is not accompanied by an itching sensation.
This section will help you learn more about HAE, including:
How your doctor will make an HAE diagnosis.
Do I Have HAE?
These questions will help you and your doctor discuss your HAE symptoms.